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A single herb for the treatment of cancer without side effects found
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The single herb, curcumin in turmeric is the potential cancer cure
Could curcumin in turmeric be the herb for the treatment of cancer? Yes, it could be. The single herb for the treatment of cancer without side effects found, which is turmeric. The natural polyphenol curcumin, a nutrient in turmeric has shown promising efficacy with cancerous tumours in a number of preclinical models, in one of our latest health education news blog posts of today, December 15, 2022.
According to the health education news report, curcumin, a natural polyphenol, has demonstrated promising efficacy as an anti-tumours in several preclinical models and could be the herb for the treatment of cancer, even though such studies have reported anecdotal evidence of curcumin’s effect in cancer patients.
In cancer clinical studies, curcumin, a natural molecular curcumin found in herbaceous turmeric, which serves as a cooking spice, has been used as anti-tumour to treat cancer patients.
Now, a team of researchers at Kyoto University, led by Masashi Kanai, has developed a prodrug form of curcumin, TBP1901, in research to find the effectiveness of the herb in the treatment of cancer, that has shown anti-tumor effects without toxicities for the treatment of the disease. The study was funded by the Japan Society for the Promotion of Science
Masashi Kanai’s team has found a possible detour around the problem by deductively identifying the enzyme GUSB for its key role in TBP1901 conversion to curcumin.
They also confirmed, using a CRISPR-Cas9 screen method, that despite the promising result the herb has for the treatment of cancer, curcumin also has essential therapeutic targets.
“The high conversion rate of TBP1901 to curcumin in bone marrow warrants its clinical application for diseases growing in the marrow like multiple myeloma and leukemia,” noted Kanai.
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How curcumin in turmeric helps in the treatment of cancer
How does curcumin found in turmeric become a herb for the treatment of cancer? The developed Prodrug curcumin displays clinical potential. The high conversion rate of curcumin prodrug TBP1901 to curcumin in bone marrow warrants its clinical application for diseases growing in the marrow like multiple myeloma and leukemia
Curcumin treats cancer without side effects
Curcumin has long been used as a spice or food coloring, and it is expected in its natural use to treat cancer with minimal or no side effects.
Curcumin, a natural polyphenol, has demonstrated promising efficacy against tumors in several preclinical models. Such studies have reported anecdotal evidence of curcumin’s effect on cancer patients.
Limitations to the use of curcumin for the treatment of cancer
Despite its known antitumor effects, drug development has lagged due to challenges involving its chemistry. Curcumin’s limited bioavailability and low stability have hampered its clinical application to date.
What is curcumin?
Curcumin is a bright yellow chemical produced by plants of the principal curcuminoid of turmeric a member of the ginger family, sold either as a herbal supplement, cosmetics ingredient, food flavouring, and food colouring.
It is approved as a food additive by the World Health Organization, European Parliament, and the United States Food and Drug Administration.
What is turmeric?
Turmeric is a flowering plant of the ginger family, a herbaceous rhizomes of which are used in cooking used fresh or boiled in water and dried, after which they are ground into a deep orange-yellow powder commonly used as a colouring and flavouring agent especially for curries, as well as for dyeing, characteristics imparted by the principal turmeric constituent, curcumin.
Turmeric powder has a warm, bitter, black pepper-like flavor and earthy, mustard-like aroma.
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The healthcare education blog post was captioned: Anti-Tumor Effects Without Toxicities: Researchers Use a Spice To Treat Cancer
Read more on SciTechDaily
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